Signal Transduction Reagents and Kits
Promega KDR Kinase Enzyme System, 1mg
Recombinant human KDR (amino acids 789-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. KDR (or kinase insert domain receptor) is a growth factor receptor tyrosine kinase originally isolated from human endothelial cells.
Promega CAMK2 alpha Kinase Enzyme System, 10microg
Recombinant full-length human CAMK2 alpha was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. CAMK2 alpha is a ser/thr protein kinase that is a member of the Ca2+/calmodulin-dependent protein kinase family.
Promega PDK1 Kinase Enzyme System, 1mg
Recombinant full-length human PDK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. PDK1 (3-phosphoinositide-dependent protein kinase) is activated by the presence of PtdIns(3,4,5)P3 or PtdIns(3,4)P2.
Promega Glutamate-Glo Assay, 50ml
The Glutamate-Glo Assay is a bioluminescent assay for rapid, selective and sensitive detection of glutamate in biological samples. The assay couples glutamate oxidation and NADH production with a bioluminescent NADH detection system.
Promega MSK2 Kinase Enzyme System, 10microg
Recombinant full-length mouse MSK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Promega IRAK4 Kinase Enzyme System, 1mg
Recombinant full-length human IRAK4 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Interleukin-1 receptor-associated kinase 4 is an important mediator in the signal transduction of Toll-like receptor and IL1R family members.
Promega CDK9/CyclinK Kinase Enzyme System, 10microg
Recombinant full-length human CDK9 and CyclinK proteins were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CDK9/CyclinK is a member of the cyclin-dependent protein kinase (CDK) family.
Promega MLK1 Kinase Enzyme System, 1mg
Recombinant human MLK1 (1-433) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Mixed-Lineage Kinase 1 is a mitogen-activated protein kinase kinase kinase capable of activating the c-Jun NH(2)-terminal kinase (JNK) pathway.
Promega CSK Kinase Enzyme System, 1mg
Recombinant full-length human CSK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CSK has been shown to downregulate the tyrosine kinase activity of c-src through tyrosine phosphorylation of the c-src carboxy terminus.
Promega TRKB Kinase Enzyme System, 1mg
Recombinant human TRKB (455-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. TRKB is a member of the neurotrophic tyrosine receptor kinase (NTRK) family.
Promega MRCK alpha Kinase Enzyme System, 1mg
Recombinant human MRCKalpha (1-473) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Promega MET Kinase Enzyme System, 1mg
Recombinant human MET (amino acids 956-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. MET is a proto-oncogene that encodes a transmembrane growth factor receptor.
Promega ADP-Glo™ Kinase Assay + p38δ Kinase Enzyme System
Recombinant full-length human p38 delta was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. It is a member of the p38 MAPK family and is activated by chemical and environmental stresses as well as by proinflammatory cytokines.
Promega PKC alpha Kinase Enzyme System, 1mg
Recombinant full-length human PKC alpha was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PKC alpha is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases.
Promega PKC beta II Kinase Enzyme System, 1mg
Recombinant full-length human PKC beta II was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PKC beta II is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases.